Scientific program 2022
program – Tuesday, November 22, 2022
9:00–10:30 am
Live Session I
Chairs: Köhl, Ulrike & Platzbecker, Uwe
Of CARs and TRUCKs: Redirected T cells for the adoptive immunotherapy
Keynote: Abken, Hinrich (RCI – University of Regensburg, Regensburg, Germany)
NK cells as "CAR" drivers – current status and future developments
Keynote: Tonn, Torsten (Technical University of Dresden, Faculty of Medicine Carl Gustav Carus, Dresden, Germany)
10:30–10:45 am
Break
10:45-11:15 am
Flash Talk I
11:15–11:30 am
Break
11:30 am – 12:15 pm
Symposium I
12:15–1:00 pm
Break
1:00-1:45 pm
Symposium II
1:45-2:15 pm
Break
2:15-3:45 pm
Live Session II
Chairs: Blache, Ulrich & Vucinic, Vladan
TCR-engineered cells for cancer immunotherapy
Keynote: Olweus, Johanna (Oslo University Hospital, Oslo, Norway)
Treatment with tumor infiltrating lymphocytes – Clinical experience and future perspectives
Keynote: Klobuch, Sebastian (Netherlands Cancer Institute, Amsterdam, The Netherlands)
3:45-4:00 pm
Break
4:00-5:00 pm
Poster Session – CAR-T cell therapy | CAR-NK cell therapy | Non-viral gene transfer | Viral vectors in immunotherapy
Moderation: Tretbar, Sandy
CRISPR/Cas9 knock-out of inhibitory receptor NKG2A improves efficacy of CD33-CAR-NK cells against AML
Bexte, Tobias
Dual targeting of CAR-NK cells to PD-L1 and HER2 facilitates specific elimination of cancer cells of solid tumor origin and overcomes immune escape by antigen loss
Eitler, Jiri
Lipid Nanoparticles as Next-Generation mRNA Delivery System for Transient CAR T Cell Therapy
Kitte, Reni
Accelerating the development and improving access to CAR- and TCR-engineered T cell therapy in Europe
Luu, Maik
Lentiviral Vector large scale manufacturing using suspension platform
Neri, Margherita
Continuous production of hiPSC-derived Natural Killer cells and Dendritic cells using a concurrent differentiation platform
Saleh, Fawaz
Optimization of lentiviral vector mediated transduction of T cells for clinical use
Vallanti, Giuliana
Short-chain fatty acids – Potential key regulators of intestinal inflammation in CAR T cell therapy
Wegner, Valentin
program – Wednesday, November 23, 2022
9:00–10:30 am
Live Session III
Chair: Lordick, Florian
CAR-T cells and solid tumors / Increasing the therapeutic index of CAR-T cells in solid tumors
Keynote: Guedan, Sonia (August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain)
The clinical implementation of immunotherapies in the treatment of gastrointestinal cancers
Keynote: Smyth, Elizabeth (Cambridge University Hospitals NHS Foundation Trust, Cambridge, Great Britain)
10:30–10:45 am
Break
10:45-11:15 am
Flash Talk II
11:15–11:30 am
Break
11:30 am – 12:15 pm
Live Session IV
Chair: Köhl, Ulrike
NK cells and the increasingly interesting concept of memory-like NK cells
Keynote: Lowdell, Mark (University College London, London, Great Britain)
12:15–1:00 pm
Break
1:00-1:45 pm
Symposium III
1:45-2:15 pm
Break
2:15-3:45 pm
Live Session V
Chairs: Hacker, Ulrich & Köhl, Ulrike
Vaccine-based approaches / mRNA therapeutics in cancer immunotherapy
Keynote: Rengstl, Benjamin (BioNTech SE, Mainz, Germany)
RO(A)Ring CAR T cells to treat hematologic and solid tumors
Keynote: Hudecek, Michael (Universitätsklinikum Würzburg, Würzburg, Germany)
3:45-4:00 pm
Break
4:00-5:00 pm
Poster Session – Open topic
Moderation: Schmiedel, Dominik
Fully standardized human immune cells as a screening platform for novel cancer immuno-therapeutics and beyond
Abdin, Shifaa
Insight into the mechanism of cellularization in cancer multikaryocytes
Dsouza, Flevy
Genetic alterations and immune cell infiltration with potential impact on PD-(L)1 targeted treatment in various cancer entities – Biobank research project of the INFINITY registry
Kasenda, Benjamin
A transcriptomic landscape of immune cells TME in early-stage lung adenocarcinoma by single-cell sequencing
Kulshreshtha, Ritika
Efficient Tumor Therapy with an Antibody Inhibiting Shedding of MIC Molecules
Liptáková, Veronika
In-vitro validation of Glypican-1 as a novel potential target for antibody- or CAR-based therapies of triple-negative breast cancer (TNBC)
Mueller, Claudia
Revealing the Mechanism of Action of the Anti-Human CD4 Antibody MAX.16H5 for Induction of Immune Tolerance
Roth, Kristina
Cell-specific contributions to differential patterns of sterile inflammation in LR-MDS
Schneider, Marie
Investigation of effects of acetylsalicylic acid on pancreatic stellate cells-mediated pancreatic cancer aggressiveness
Sığırlı, Sıla
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